SCHEMBL28856430

SCHEMBL28856430

NC(=O)c1ccc(OCC(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 13/20 0.65
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
PARP15 Q460N3 4/20 0.51
PARP14 Q460N5 2/20 0.51
MAOB P27338 2/20 0.51
PARP2 Q9UGN5 1/20 0.49
ALDH1A1 P00352 1/20 0.48
KMT2A Q03164 1/20 0.48
PARP16 Q8N5Y8 1/20 0.48
PARP11 Q9NR21 1/20 0.48
PARP4 Q9UKK3 1/20 0.48
POLB P06746 1/20 0.48
CYP3A4 P08684 1/20 0.48
PARP1 P09874 1/20 0.48
MAPT P10636 1/20 0.48
TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7321136 0.86 PKM (0.62) CA12CA1CA2CA7CA9
SCHEMBL9815480 0.82 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL7321684 0.78 MAPT (0.61) CA12CA1CA2CA7CA9
SCHEMBL6566065 0.78 SCN4A (0.65) CA12CA1CA2CA7CA9
SCHEMBL17341985 0.77 PARP10 (0.65) PARP10CA1CA2PARP15PARP14
SCHEMBL29721331 0.77 CA12 (0.57) CA12CA1CA2CA7CA9
Benzamide SCHEMBL5531824 0.76 PARP10 (0.86) PARP10PARP15PARP14MAOBKMT2A
SCHEMBL10609453 0.76 PARP10 (0.62) PARP10CA1CA2PARP15PARP14
SCHEMBL119689 0.76 PARP10 (1.00) PARP10PARP15PARP14MAOBCYP2C19
SCHEMBL30151821 0.76 PARP10 (0.62) PARP10CA1CA2PARP15PARP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107790186-A A kind of new decamethyl Zirconocenes and its preparation method and application 山西医科大学 2018-03-13 CN disclosed