Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5974518 | 0.95 | — | — | |
| Bicarbonate SCHEMBL28502389 | 0.95 | LMNA (0.54) | — | |
| Bicarbonate SCHEMBL10778055 | 0.84 | LMNA (0.44) | — | |
| Acetic Acid SCHEMBL4820061 | 0.84 | — | — | |
| Bicarbonate SCHEMBL27856188 | 0.82 | — | — | |
| SCHEMBL28293011 | 0.82 | — | — | |
| Butadiene SCHEMBL28898214 | 0.82 | LMNA (0.50) | — | |
| Ethylene SCHEMBL3853622 | 0.80 | TSHR (0.33) | — | |
| Bicarbonate SCHEMBL10831385 | 0.80 | CA1 (0.71) | — | |
| Ethylene SCHEMBL5276152 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103957887-B | ophthalmic composition comprising prostaglandin F2 α derivative and hyaluronic acid | R·哈德-斯利梅恩 | 2018-02-06 | — | — | CN | disclosed |