Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 18/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856529 | 0.86 | TP53 (0.33) | PPARASLC22A12 | |
| SCHEMBL28856538 | 0.85 | SLC22A12 (0.53) | PPARASLC22A12CYP1A2SLC22A6SLC22A11 | |
| SCHEMBL28856513 | 0.84 | SLC22A12 (0.54) | PPARASLC22A12CYP1A2CYP2C9SLC22A6 | |
| SCHEMBL28856548 | 0.81 | PPARA (0.47) | PPARASLC22A12SLC22A6SLC22A11 | |
| SCHEMBL28856528 | 0.81 | SLC22A12 (0.57) | PPARASLC22A12SLC22A6SLC22A11 | |
| SCHEMBL28856558 | 0.80 | SLC22A12 (0.49) | PPARASLC22A12CYP1A2CYP2C9SLC22A6 | |
| SCHEMBL28856531 | 0.78 | SLC22A12 (0.58) | PPARASLC22A12SLC22A6SLC22A11 | |
| SCHEMBL28856519 | 0.75 | SLC22A12 (0.38) | PPARASLC22A12 | |
| SCHEMBL28856487 | 0.73 | GRM2 (0.31) | — | |
| SCHEMBL28856520 | 0.73 | SLC22A12 (0.39) | PPARASLC22A12CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |