Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 19/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856493 | 0.85 | SLC22A12 (0.38) | SLC22A12 | |
| SCHEMBL28856538 | 0.82 | SLC22A12 (0.53) | SLC22A12PPARASLC22A11SLC22A6CYP1A2 | |
| SCHEMBL28856513 | 0.81 | SLC22A12 (0.54) | SLC22A12PPARASLC22A11SLC22A6CYP1A2 | |
| SCHEMBL28856492 | 0.80 | PPARA (0.48) | SLC22A12PPARASLC22A11SLC22A6CYP1A2 | |
| SCHEMBL28856548 | 0.79 | PPARA (0.47) | SLC22A12PPARASLC22A11SLC22A6 | |
| SCHEMBL28856528 | 0.78 | SLC22A12 (0.57) | SLC22A12PPARASLC22A11SLC22A6 | |
| SCHEMBL28856521 | 0.76 | SLC22A12 (0.33) | SLC22A12SLC22A11CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28856504 | 0.76 | SLC22A12 (0.33) | SLC22A12SLC22A11CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28856531 | 0.75 | SLC22A12 (0.58) | SLC22A12PPARASLC22A11SLC22A6 | |
| SCHEMBL28856516 | 0.74 | KDM4E (0.33) | SLC22A12SLC22A11CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |