Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.33 |
| ▸ | KCNK4 | Q9NYG8 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856490 | 0.89 | SLC22A12 (0.40) | SLC22A12NPC1KMT2ACAMKK1CAMKK2 | |
| SCHEMBL28856507 | 0.89 | SLC22A12 (0.39) | SLC22A12 | |
| SCHEMBL28954997 | 0.88 | SLC22A12 (0.42) | SLC22A12CAMKK1CAMKK2 | |
| SCHEMBL28856557 | 0.88 | SLC22A12 (0.34) | SLC22A12PTGDR2HTR1AADRA1DADRA1A | |
| SCHEMBL28856496 | 0.86 | CA12 (0.39) | SLC22A12PTGDR2NPC1RAB9AKMT2A | |
| SCHEMBL28856509 | 0.86 | SLC22A12 (0.41) | SLC22A12ACVR1ABL1 | |
| SCHEMBL28856546 | 0.83 | SLC22A12 (0.40) | SLC22A12NPC1KMT2ACAMKK1CAMKK2 | |
| SCHEMBL28856491 | 0.83 | SLC22A12 (0.39) | SLC22A12NPC1KMT2ARXFP1 | |
| SCHEMBL28856565 | 0.82 | SLC22A12 (0.41) | SLC22A12NPC1RAB9AKMT2ACAMKK1 | |
| SCHEMBL28856483 | 0.80 | SMN1; SMN2 (0.34) | SLC22A12NPC1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |