Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856508 | 0.86 | SLC22A12 (0.39) | CAMKK1CAMKK2NPC1TP53MAPT | |
| SCHEMBL28856507 | 0.85 | SLC22A12 (0.39) | SLC22A12IDO1 | |
| SCHEMBL28856490 | 0.85 | SLC22A12 (0.40) | CAMKK1CAMKK2SMN1; SMN2NPC1TP53 | |
| SCHEMBL28856491 | 0.85 | SLC22A12 (0.39) | NPC1SLC22A12KMT2A | |
| SCHEMBL28856505 | 0.85 | ALDH1A1 (0.35) | CA12CA1CA2CA9CAMKK1 | |
| SCHEMBL28954997 | 0.85 | SLC22A12 (0.42) | CAMKK1CAMKK2SLC22A12 | |
| SCHEMBL28856509 | 0.83 | SLC22A12 (0.41) | SLC22A12ACVR1IDO1 | |
| SCHEMBL28856553 | 0.81 | SLC22A12 (0.31) | SLC22A12 | |
| SCHEMBL28955000 | 0.81 | HPGD (0.34) | MAPTSLC22A12LMNAMAPK1KMT2A | |
| SCHEMBL28856504 | 0.80 | SLC22A12 (0.33) | SLC22A12CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |