Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 5/20 | 0.67 |
| ▸ | CDK1 | P06493 | 5/20 | 0.67 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.67 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.67 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.57 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.57 |
| ▸ | CDK4 | P11802 | 2/20 | 0.56 |
| ▸ | GSK3B | P49841 | 2/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 5/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | RET | P07949 | 5/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823463 | 0.94 | MAPK8 (0.62) | CCNB2CDK1CCNB1CCNB3MKNK2 | |
| SCHEMBL3824605 | 0.94 | MAPK8 (0.62) | CCNB2CDK1CCNB1CCNB3MKNK2 | |
| SCHEMBL14193549 | 0.94 | CDK1 (0.76) | CCNB2CDK1CCNB1CCNB3MKNK2 | |
| SCHEMBL3478495 | 0.86 | CCNB2 (0.53) | CCNB2CDK1CCNB1CCNB3MKNK2 | |
| SCHEMBL28857038 | 0.82 | MKNK1 (0.64) | CCNB2CDK1CCNB1CCNB3MKNK2 | |
| SCHEMBL13638545 | 0.81 | CCNB2 (0.48) | CCNB2CDK1CCNB1CCNB3MKNK2 | |
| SCHEMBL3776164 | 0.81 | CCNB2 (0.80) | CCNB2CDK1CCNB1CCNB3MKNK2 | |
| SCHEMBL3776172 | 0.81 | CCNB2 (0.80) | CCNB2CDK1CCNB1CCNB3MKNK2 | |
| SCHEMBL3775441 | 0.80 | CDK1 (1.00) | CCNB2CDK1CCNB1CCNB3MKNK2 | |
| SCHEMBL30129265 | 0.80 | MKNK1 (0.56) | CCNB2CDK1CCNB1CCNB3MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563310-B | 4- (1-methylindol-3-yl) pyrimidine derivative and application thereof | 浙江工业大学 | 2022-10-11 | — | — | CN | disclosed |