Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | HTR6 | P50406 | 16/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21569660 | 0.84 | MEN1 (0.65) | MEN1KMT2AHTR6ALDH1A1LMNA | |
| SCHEMBL29560121 | 0.84 | MEN1 (0.65) | MEN1KMT2AHTR6ALDH1A1LMNA | |
| SCHEMBL29559974 | 0.82 | MEN1 (1.00) | MEN1KMT2AHTR6ALDH1A1LMNA | |
| SCHEMBL10345778 | 0.82 | MEN1 (1.00) | MEN1KMT2AHTR6ALDH1A1LMNA | |
| SCHEMBL45741 | 0.80 | HTR6 (0.63) | MEN1KMT2AHTR6ALDH1A1LMNA | |
| SCHEMBL31319736 | 0.80 | HTR6 (0.63) | MEN1KMT2AHTR6ALDH1A1LMNA | |
| SCHEMBL28920261 | 0.80 | MEN1 (0.67) | MEN1KMT2AHTR6ALDH1A1LMNA | |
| SCHEMBL17597311 | 0.78 | MEN1 (0.85) | MEN1KMT2AHTR6ALDH1A1LMNA | |
| SCHEMBL6851383 | 0.78 | MEN1 (0.68) | MEN1KMT2AHTR6ALDH1A1LMNA | |
| SCHEMBL27879729 | 0.78 | MEN1 (0.72) | MEN1KMT2AHTR6ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107820494-A | Nuclear receptor modulators | 艾伯维公司 | 2018-03-20 | — | — | CN | disclosed |