Benzene

Benzene

SCHEMBL28857433

C1=Nc2cccnc2C1.c1ccccc1

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 1/20 0.34
PDE3A Q14432 1/20 0.34
LMNA P02545 2/20 0.31
NAPRT Q6XQN6 1/20 0.31
P4HTM Q9NXG6 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDM4E B2RXH2 4/20 0.31
MAPT P10636 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
GMNN O75496 1/20 0.31
TP53 P04637 1/20 0.31
HSP90AA1 P07900 1/20 0.31
MMP2 P08253 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
MMP9 P14780 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
MMP8 P22894 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31001732 0.98
SCHEMBL2439123 0.98
Hydrochloric Acid SCHEMBL28075122 0.95 PDE3B (0.34) PDE3BPDE3ALMNAKDM4EMAPT
Hydrochloric Acid SCHEMBL28108450 0.93 PDE3B (0.33) PDE3BPDE3ALMNAKDM4EMAPT
Hydrochloric Acid SCHEMBL28102530 0.79 PDE3B (0.33) PDE3BPDE3A
Tert-Butyl Formate SCHEMBL28081848 0.78 TDP1 (0.39) TDP1
SCHEMBL4769982 0.76 CYP19A1 (0.33) PDE3BPDE3ALMNAKDM4EMAPT
SCHEMBL1020681 0.71 TDP2 (0.41) PDE3BPDE3AKDM4ETDP1GAA
SCHEMBL2501190 0.70 PDE3B (0.33) PDE3BPDE3A
SCHEMBL7074142 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107778495-A A kind of cadmium metal organic frame complex and preparation method thereof 宁波大学 2018-03-09 CN disclosed