Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 18/20 | 0.60 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16098380 | 0.87 | WNT3A (0.61) | WNT3AKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL16098943 | 0.83 | WNT3A (0.57) | WNT3AKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL16098546 | 0.82 | WNT3A (0.72) | WNT3A | |
| SCHEMBL20653086 | 0.80 | PTPN1 (0.67) | WNT3AKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL16099159 | 0.80 | WNT3A (0.61) | WNT3A | |
| SCHEMBL28207102 | 0.79 | PTPN1 (0.66) | WNT3AKCNQ3KCNQ2 | |
| SCHEMBL5934707 | 0.78 | MAPT (0.61) | WNT3AKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL5934792 | 0.77 | TRPV1 (0.62) | WNT3AKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL16098909 | 0.77 | WNT3A (0.58) | WNT3A | |
| SCHEMBL5934547 | 0.77 | PTPN1 (0.61) | WNT3AKCNQ3KCNQ2KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105228982-B | 3-acetylamino-1- (phenyl-heteroaryl-aminocarbonyl or phenyl-heteroaryl-carbonylamino) benzene derivatives for the treatment of hyperproliferative disorders | 拜耳制药股份公司 | 2018-03-27 | — | — | CN | disclosed |