Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29898258 | 0.87 | POLB (0.49) | POLBMAPTHPGDALDH1A1MEN1 | |
| SCHEMBL28857616 | 0.87 | POLB (0.49) | POLBMAPTHPGDALDH1A1MEN1 | |
| SCHEMBL28857641 | 0.87 | SMN1; SMN2 (0.51) | POLBSMN1; SMN2LMNAKDM4EHTT | |
| SCHEMBL29898279 | 0.86 | KMT2A (0.49) | POLBMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28857586 | 0.86 | KMT2A (0.49) | POLBMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28857639 | 0.85 | HTT (0.53) | POLBALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29898218 | 0.84 | POLB (0.47) | POLBHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28857659 | 0.84 | POLB (0.50) | POLBMAPTHPGDALDH1A1MEN1 | |
| SCHEMBL29898221 | 0.84 | SMN1; SMN2 (0.46) | POLBHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28857607 | 0.84 | SMN1; SMN2 (0.46) | POLBHPGDMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | claimed |
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | disclosed |