Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.41 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29898221 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBLMNAHTTKDM4E | |
| SCHEMBL28857586 | 0.90 | KMT2A (0.49) | SMN1; SMN2POLBLMNAMEN1TSHR | |
| SCHEMBL29898279 | 0.90 | KMT2A (0.49) | SMN1; SMN2POLBLMNAMEN1TSHR | |
| SCHEMBL28857587 | 0.88 | POLB (0.47) | SMN1; SMN2POLBLMNAHTTKCNJ6 | |
| SCHEMBL29898218 | 0.88 | POLB (0.47) | SMN1; SMN2POLBLMNAHTTKCNJ6 | |
| SCHEMBL28857641 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2POLBLMNAHTTKDM4E | |
| SCHEMBL29898258 | 0.84 | POLB (0.49) | SMN1; SMN2POLBLMNAHTTHPGD | |
| SCHEMBL28857616 | 0.84 | POLB (0.49) | SMN1; SMN2POLBLMNAHTTHPGD | |
| SCHEMBL28857590 | 0.84 | POLB (0.51) | SMN1; SMN2POLBLMNAHTTKDM4E | |
| SCHEMBL28857620 | 0.83 | TNIK (0.49) | SMN1; SMN2POLBLMNAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | claimed |
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | disclosed |