Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11984343 | 0.83 | HPGD (0.56) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL1401544 | 0.83 | LMNA (0.53) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL2162352 | 0.83 | HPGD (0.51) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL1311028 | 0.81 | MRGPRX4 (0.54) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL14114132 | 0.81 | LMNA (0.51) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL14135378 | 0.81 | LMNA (0.51) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL16812822 | 0.81 | MRGPRX4 (0.57) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL348559 | 0.81 | LMNA (0.51) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL1977403 | 0.81 | NPSR1 (0.51) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL13675115 | 0.80 | DAO (0.48) | LMNAHPGDMRGPRX4TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | disclosed |