Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | CPA3 | P15088 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 3/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877114 | 0.84 | LAP3 (0.36) | CYP1A2SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL6946871 | 0.80 | CYP1A2 (0.39) | CYP1A2EPHX1ALPIPKMPTGS1 | |
| SCHEMBL9725521 | 0.80 | TAAR1 (0.45) | CYP1A2SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL6441941 | 0.77 | EPHX1 (0.52) | CYP1A2EPHX1ALPIPKMPTGS1 | |
| SCHEMBL19812645 | 0.76 | EPHX1 (0.43) | CYP1A2EPHX1ALPIPKMPTGS1 | |
| SCHEMBL367322 | 0.76 | LAP3 (0.38) | CYP1A2EPHX1SLC6A2TAAR1MAOA | |
| SCHEMBL4981467 | 0.74 | EPHX1 (0.60) | CYP1A2EPHX1ALPIPKMPTGS1 | |
| SCHEMBL7864719 | 0.73 | TAAR1 (0.42) | CYP1A2SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL24108632 | 0.73 | EPHX1 (0.48) | CYP1A2EPHX1SLC6A2TAAR1MAOA | |
| SCHEMBL7085691 | 0.73 | EPHX1 (0.48) | EPHX1SLC6A2TAAR1MAOASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107802623-A | For the bone related disease of EP4 mediations and the difluoro lactam composition of illness | 开曼化学股份有限公司 | 2018-03-16 | — | — | CN | disclosed |