Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13212542 | 0.85 | TDP1 (0.43) | TDP1TP53KDM4EGAAMAPT | |
| SCHEMBL5376758 | 0.84 | CES2 (0.55) | TDP1TP53MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29503054 | 0.84 | CES2 (0.55) | TDP1TP53MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7096163 | 0.82 | CA12 (0.61) | KDM4EGAAMAPTCA12CA1 | |
| SCHEMBL29503047 | 0.82 | CA12 (0.61) | KDM4EGAAMAPTCA12CA1 | |
| SCHEMBL11429888 | 0.80 | CES2 (0.50) | TDP1TP53KDM4EGAAMAPT | |
| SCHEMBL172420 | 0.79 | CA12 (0.64) | TDP1TP53KDM4EGAAMAPT | |
| SCHEMBL29979976 | 0.79 | CA12 (0.64) | TDP1TP53KDM4EGAAMAPT | |
| SCHEMBL7490868 | 0.78 | CA1 (0.42) | KDM4EMAPTALDH1A1KMT2ACA1 | |
| SCHEMBL31621156 | 0.77 | HTT (0.61) | TDP1TP53MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108047048-A | A kind of benzenpropanoic acid ester type compound and its preparation method and application | 苏州沪云肿瘤研究中心股份有限公司 | 2018-05-18 | — | — | CN | disclosed |