Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10076406 | 0.87 | ATM (0.58) | ATML3MBTL1KMT2ANOS3NOS1 | |
| SCHEMBL28803420 | 0.85 | ATM (0.49) | ATMTACR1NOS3NOS1NOS2 | |
| SCHEMBL14190610 | 0.84 | ATM (0.46) | ATML3MBTL1PPARGTDP1ACACB | |
| SCHEMBL26079891 | 0.83 | ATM (0.48) | ATML3MBTL1PPARGTDP1ACACB | |
| SCHEMBL9886030 | 0.80 | ACACB (0.46) | ATML3MBTL1PPARGTDP1ACACB | |
| SCHEMBL12668874 | 0.80 | ACACB (0.46) | ATML3MBTL1PPARGTDP1ACACB | |
| SCHEMBL9886036 | 0.80 | TDP1 (0.55) | ATML3MBTL1PPARGTDP1PPARA | |
| SCHEMBL805206 | 0.80 | TDP1 (0.55) | ATML3MBTL1PPARGTDP1PPARA | |
| SCHEMBL9886029 | 0.78 | TDP1 (0.43) | ATML3MBTL1PPARGTDP1ACACB | |
| SCHEMBL26304810 | 0.78 | MMP1 (0.43) | ATML3MBTL1TDP1ACACBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849018-A | Bridged piperazine derivatives | 安斯泰来制药株式会社 | 2018-03-27 | — | — | CN | disclosed |