SCHEMBL28858558

SCHEMBL28858558

ClC(CBr)Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.46
TRPA1 O75762 1/20 0.46
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
TAAR1 Q96RJ0 4/20 0.43
SLC6A2 P23975 2/20 0.43
SIGMAR1 Q99720 2/20 0.43
MAOA P21397 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
CYP2A6 P11509 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
CYP1A2 P05177 1/20 0.41
SLC18A2 Q05940 1/20 0.40
ANPEP P15144 1/20 0.40
CYP2D6 P10635 1/20 0.40
CPA1 P15085 1/20 0.40
ALPI P09923 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6685343 0.78 EPHX1 (0.48) EPHX1TRPA1TAAR1SLC6A2SIGMAR1
SCHEMBL11445194 0.77 TDP1 (0.40) EPHX1TRPA1ALDH1A1TSHRTAAR1
SCHEMBL28858512 0.76 EPHX1 (0.46) EPHX1TRPA1ALDH1A1TAAR1SLC6A2
SCHEMBL9171314 0.76 TRPA1 (0.54) EPHX1TRPA1TSHRTAAR1SLC6A2
SCHEMBL7472740 0.76 TRPA1 (0.54) EPHX1TRPA1TSHRTAAR1SLC6A2
SCHEMBL2241799 0.76 TRPA1 (0.50) EPHX1TRPA1TAAR1SLC6A2SIGMAR1
SCHEMBL10544290 0.76 CYP1A2 (0.46) EPHX1TAAR1SLC6A2SIGMAR1MAOA
SCHEMBL27697899 0.76 EPHX1 (0.46) EPHX1TRPA1TAAR1SLC6A2SIGMAR1
SCHEMBL4082647 0.76 EPHX1 (0.41) EPHX1TRPA1ALDH1A1TSHRTAAR1
SCHEMBL1278885 0.75 EPHX1 (0.50) EPHX1TRPA1ALDH1A1TSHRTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115197046-B Halogenation method of unsaturated hydrocarbon 华南理工大学 2023-12-15 CN disclosed
CN-115197046-A Halogenation method of unsaturated hydrocarbon 华南理工大学 2022-10-18 CN disclosed