SCHEMBL28858563

SCHEMBL28858563

Br/C(I)=C(\I)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.39
CES2 O00748 3/20 0.39
TSHR P16473 2/20 0.39
ALDH1A1 P00352 2/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
PTPN1 P18031 1/20 0.37
GSK3B P49841 1/20 0.37
TDP1 Q9NUW8 3/20 0.36
F2 P00734 2/20 0.36
CYP3A4 P08684 2/20 0.36
MAPT P10636 2/20 0.36
BLM P54132 2/20 0.36
CA2 P00918 2/20 0.36
CA4 P22748 2/20 0.36
F10 P00742 1/20 0.36
F12 P00748 1/20 0.36
F7 P08709 1/20 0.36
F3 P13726 1/20 0.36
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10954058 1.00 CES1 (0.39) CES1CES2TSHRALDH1A1DAO
SCHEMBL10454311 0.82 CES1 (0.47) CES1CES2TSHRALDH1A1DAO
SCHEMBL10893693 0.82 CES1 (0.47) CES1CES2TSHRALDH1A1DAO
SCHEMBL28858554 0.79 ALDH1A1 (0.42) CES1CES2TSHRALDH1A1DAO
SCHEMBL28858549 0.79 ALDH1A1 (0.42) CES1CES2TSHRALDH1A1DAO
SCHEMBL9579634 0.77 CES1 (0.43) CES1CES2TSHRALDH1A1DAO
SCHEMBL31264146 0.77 CES1 (0.43) CES1CES2TSHRALDH1A1DAO
SCHEMBL12097248 0.77
SCHEMBL18872063 0.76 CES1 (0.38) CES1CES2TSHRALDH1A1DAO
SCHEMBL17230463 0.76 CES1 (0.38) CES1CES2TSHRALDH1A1DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115197046-B Halogenation method of unsaturated hydrocarbon 华南理工大学 2023-12-15 CN disclosed
CN-115197046-A Halogenation method of unsaturated hydrocarbon 华南理工大学 2022-10-18 CN disclosed