SCHEMBL28858657

SCHEMBL28858657

Cc1ccc(CCCc2ccc(C)cc2O)c(O)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 5/20 0.53
TRPA1 O75762 2/20 0.52
ALOX15 P16050 4/20 0.50
TP53 P04637 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
MEN1 O00255 2/20 0.50
MAPT P10636 2/20 0.50
KMT2A Q03164 2/20 0.50
CYP3A4 P08684 1/20 0.50
ALOX5 P09917 1/20 0.50
TSHR P16473 1/20 0.50
HTT P42858 1/20 0.50
ESR1 P03372 1/20 0.47
CYP19A1 P11511 1/20 0.47
ESR2 Q92731 1/20 0.47
AMY1A P0DUB6 1/20 0.44
LMNA P02545 2/20 0.43
CHRM1 P11229 1/20 0.43
SLC6A2 P23975 1/20 0.43
ADRA1A P35348 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8400481 0.93 TYR (0.58) TYRTRPA1ALOX15TP53TDP1
SCHEMBL14001444 0.92 TYR (0.67) TYRALOX15TP53TDP1MEN1
SCHEMBL10914582 0.90 TYR (0.48) TYRTRPA1ALOX15TP53TDP1
SCHEMBL901087 0.90 TYR (0.69) TYRTRPA1ALOX15TP53TDP1
Butane SCHEMBL28342368 0.88 TYR (0.67) TYRTRPA1ALOX15TP53TDP1
Amylmetacresol SCHEMBL302197 0.88 TYR (0.68) TYRTRPA1ALOX15TP53TDP1
Amylmetacresol SCHEMBL29897625 0.88 TYR (0.68) TYRTRPA1ALOX15TP53TDP1
SCHEMBL7065825 0.87 ESR1 (0.50) TYRALOX15ALOX5ESR1CYP19A1
SCHEMBL3358965 0.86 TYR (0.71) TYRALOX15TP53TDP1MEN1
SCHEMBL9504248 0.86 TYR (0.71) TYRALOX15TP53TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108884574-B Coating agent for forming metal oxide film and method for producing substrate having metal oxide film 东京应化工业株式会社 2022-10-14 CN disclosed