Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 6/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28858657 | 0.93 | TYR (0.53) | TYRALOX15TP53TDP1MEN1 | |
| SCHEMBL574033 | 0.92 | TYR (0.51) | TYRALOX15TP53TDP1MEN1 | |
| SCHEMBL9504248 | 0.92 | TYR (0.71) | TYRALOX15TP53TDP1MEN1 | |
| SCHEMBL8590686 | 0.92 | TYR (0.71) | TYRALOX15TP53TDP1MEN1 | |
| SCHEMBL8402868 | 0.92 | TYR (0.71) | TYRALOX15TP53TDP1MEN1 | |
| SCHEMBL3358965 | 0.92 | TYR (0.71) | TYRALOX15TP53TDP1MEN1 | |
| SCHEMBL1272901 | 0.91 | TYR (0.50) | TYRALOX15TP53TDP1MEN1 | |
| Amylmetacresol SCHEMBL29897625 | 0.90 | TYR (0.68) | TYRALOX15TP53TDP1MEN1 | |
| Amylmetacresol SCHEMBL302197 | 0.90 | TYR (0.68) | TYRALOX15TP53TDP1MEN1 | |
| SCHEMBL10914582 | 0.88 | TYR (0.48) | TYRALOX15TP53TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859067-A | PREPARING BIS(2-HYDROXY-1-NAPHTHYL)DECANE FROM THE CORRESPONDING DIACID; FORMING ACID DICHLORIDE; TREATING WITH 2-NAPHTHOL; REARRANGEMENT; REDUCTION; INHIBITS ACTION OF ADENOSINE TRIPHOSPHATASE | ROUFOGALIS BASIL DON (AU) | 1999-01-12 | — | — | US | disclosed |
| US-5741821-A | PHENOLIC ENZYME INHIBITORS | THE UNIVERSITY OF SYDNEY (AU) | 1998-04-21 | — | — | US | disclosed |
| WO-1994028886-A1 | USE OF NATURAL PRODUCTS AND RELATED SYNTHETIC COMPOUNDS FOR THE TREATMENT OF CARDIOVASCULAR DISEASE | THE UNIVERSITY OF SYDNEY (AU) | 1994-12-22 | — | — | WO | disclosed |