Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.46 |
| ▸ | LPL | P06858 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 11/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 11/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | CPN1 | P15169 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768087 | 0.83 | LIPG (0.47) | LIPGLPLAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1658478 | 0.82 | PTGS1 (0.48) | LIPGLPLAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL16397301 | 0.78 | LIPG (0.40) | LIPGLPLP4HBROCK1 | |
| SCHEMBL12503163 | 0.77 | LIPG (0.45) | LIPGLPLP4HBROCK1 | |
| SCHEMBL20288359 | 0.77 | LIPG (0.50) | LIPGLPL | |
| SCHEMBL20288427 | 0.77 | LIPG (0.50) | LIPGLPL | |
| SCHEMBL27179468 | 0.77 | LIPG (0.42) | LIPGLPLP4HBROCK1 | |
| SCHEMBL27179471 | 0.77 | LIPG (0.42) | LIPGLPLP4HBROCK1 | |
| SCHEMBL22898355 | 0.77 | NPC1 (0.36) | LIPGLPL | |
| SCHEMBL26217602 | 0.76 | LIPG (0.49) | LIPGLPLROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683598-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-113683598-A | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-11-23 | — | — | CN | disclosed |