Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL28015284 | 0.87 | MAPT (0.39) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL34295 | 0.87 | GAA (0.48) | MAPTGAA | |
| SCHEMBL29415525 | 0.87 | GAA (0.48) | MAPTGAA | |
| SCHEMBL28320372 | 0.85 | GAA (0.46) | MAPTGAA | |
| SCHEMBL28397446 | 0.85 | GAA (0.46) | MAPTGAA | |
| Hydrochloric Acid SCHEMBL27563992 | 0.85 | GAA (0.46) | MAPTGAA | |
| SCHEMBL9683514 | 0.85 | GAA (0.46) | MAPTGAA | |
| Potassium SCHEMBL9683518 | 0.85 | GAA (0.46) | MAPTGAA | |
| SCHEMBL29587280 | 0.85 | GAA (0.46) | MAPTGAA | |
| Acetone SCHEMBL27943930 | 0.83 | MAPT (0.35) | MAPTGAARAB9ASMN1; SMN2P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108034119-A | Bubble bags material | 广东天元实业集团股份有限公司 | 2018-05-15 | — | — | CN | disclosed |