Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980380 | 0.79 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL1267540 | 0.75 | KMT2A (0.39) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL11537330 | 0.75 | SLC6A2 (0.35) | — | |
| SCHEMBL2625534 | 0.74 | KMT2A (0.37) | KMT2AMEN1KDM4EALDH1A1LMNA | |
| SCHEMBL2625532 | 0.74 | KMT2A (0.37) | KMT2AMEN1KDM4EALDH1A1LMNA | |
| SCHEMBL329518 | 0.74 | KMT2A (0.38) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL2622404 | 0.74 | KMT2A (0.37) | KMT2AMEN1KDM4EALDH1A1LMNA | |
| SCHEMBL10340048 | 0.71 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL23766537 | 0.71 | KMT2A (0.35) | KMT2AMEN1KDM4EALDH1A1LMNA | |
| SCHEMBL8760246 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101870-A | A kind of active ingredient of selective therapy glaucoma and its preparation method of associated salts | 盐城师范学院 | 2018-06-01 | — | — | CN | disclosed |