Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.69 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.69 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057191 | 0.88 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL28225383 | 0.87 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL28224653 | 0.85 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL7420647 | 0.82 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL11530085 | 0.81 | GLA (0.70) | GLA | |
| SCHEMBL6752134 | 0.77 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL7417324 | 0.76 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL28929058 | 0.76 | TSHR (0.61) | LMNATSHRHTTRECQLCNR1 | |
| SCHEMBL6122941 | 0.72 | TSHR (0.72) | LMNATSHRHTTRECQLCNR1 | |
| SCHEMBL18884495 | 0.71 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108164503-B | A kind of heteroaromatic and the disubstituted benzenesulfonamides of alkyl side chain and its preparing the application in anti-influenza A virus medicament | 武汉大学 | 2019-09-17 | — | — | CN | disclosed |
| CN-108164503-A | A kind of heteroaromatic and the disubstituted benzenesulfonamides of alkyl side chain and its application in anti-influenza A virus medicament is prepared | 武汉大学 | 2018-06-15 | — | — | CN | disclosed |