Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.65 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.65 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28860752 | 0.88 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL28224653 | 0.84 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL6752134 | 0.84 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL28225383 | 0.82 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL11421662 | 0.80 | ALDH1A1 (0.46) | — | |
| SCHEMBL7420647 | 0.79 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL6122941 | 0.74 | TSHR (0.72) | LMNATSHRHTT | |
| SCHEMBL7417324 | 0.73 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL18884495 | 0.73 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL11532888 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307432-A1 | CYCLIC OXYGUANIDINE PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002012207-A1 | CYCLIC OXYGUANIDINE PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2002-02-14 | — | — | WO | disclosed |