Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14774773 | 0.76 | ALDH1A1 (1.00) | ALDH1A1KMT2ARECQLPOLBHPGD | |
| SCHEMBL14774760 | 0.76 | ALDH1A1 (1.00) | ALDH1A1KMT2ARECQLPOLBHPGD | |
| SCHEMBL14774709 | 0.74 | ALDH1A1 (0.85) | ALDH1A1KMT2ARECQLPOLBHPGD | |
| SCHEMBL14774734 | 0.74 | ALDH1A1 (0.85) | ALDH1A1KMT2ARECQLPOLBHPGD | |
| SCHEMBL11263779 | 0.74 | ALDH1A1 (0.64) | ALDH1A1KMT2ARECQLPOLBHPGD | |
| SCHEMBL14774675 | 0.74 | ALDH1A1 (0.75) | ALDH1A1KMT2ARECQLPOLBHPGD | |
| SCHEMBL14774891 | 0.74 | ALDH1A1 (0.75) | ALDH1A1KMT2ARECQLPOLBHPGD | |
| SCHEMBL4331992 | 0.73 | ALDH1A1 (0.60) | ALDH1A1KMT2ARECQLPOLBHPGD | |
| SCHEMBL13236778 | 0.73 | ALDH1A1 (0.75) | ALDH1A1KMT2ARECQLPOLBHPGD | |
| SCHEMBL14774710 | 0.73 | KMT2A (0.88) | ALDH1A1KMT2ARECQLPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541773-B | A kind of preparation method of 3,4- dihydros -4- aryl-coumarin class compounds | 山东省医学科学院药物研究所 | 2018-06-29 | — | — | CN | disclosed |