⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18457583 | 0.92 | TSHR (0.46) | — | |
| SCHEMBL2880484 | 0.82 | — | — | |
| SCHEMBL2883356 | 0.81 | TSHR (0.38) | — | |
| SCHEMBL2883930 | 0.81 | TSHR (0.38) | — | |
| SCHEMBL17859929 | 0.79 | TDP1 (0.43) | — | |
| SCHEMBL17073505 | 0.77 | DNM1 (0.50) | — | |
| SCHEMBL30368694 | 0.77 | TSHR (0.43) | — | |
| SCHEMBL181351 | 0.77 | TSHR (0.43) | — | |
| SCHEMBL181420 | 0.77 | — | — | |
| SCHEMBL29438743 | 0.74 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4272832-A2 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Lakewood Amedex, Inc. (US) | 2023-11-08 | — | — | EP | disclosed |
| EP-3267794-B1 | BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | UNIV YALE (US) | 2020-09-09 | — | — | EP | disclosed |
| US-7670753-B2 | Lithographic printing plate precursor | EASTMAN KODAK COMPANY (US) | 2010-03-02 | — | — | US | disclosed |
| US-20080261146-A1 | Lithographic Printing Plate Precursor | EASTMAN KODAK COMPANY | 2008-10-23 | — | — | US | disclosed |
| EP-1782127-B1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | EASTMAN KODAK CO (US) | 2008-04-02 | — | — | EP | disclosed |