Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL27774084 | 0.80 | ALDH1A1 (0.35) | DGAT1ALDH1A1SMN1; SMN2GLARECQL | |
| SCHEMBL4328011 | 0.80 | — | — | |
| SCHEMBL15139 | 0.80 | — | — | |
| Ammonia Solution, Strong SCHEMBL243818 | 0.77 | — | — | |
| Iodide SCHEMBL9839224 | 0.77 | — | — | |
| Phosphine SCHEMBL27995477 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL13717027 | 0.77 | — | — | |
| Water SCHEMBL27758980 | 0.77 | — | — | |
| Tetrahydrofuran SCHEMBL11884252 | 0.75 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2GLAKDM4ERECQL | |
| Tetrahydrofuran SCHEMBL10761380 | 0.75 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2GLAKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341820-A | JAK enzyme inhibitors and its preparation method and application | 上海长森药业有限公司 | 2018-07-31 | — | — | CN | disclosed |