Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.49 |
| ▸ | BTK | Q06187 | 6/20 | 0.48 |
| ▸ | LCK | P06239 | 2/20 | 0.48 |
| ▸ | EML4 | Q9HC35 | 4/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.47 |
| ▸ | RET | P07949 | 3/20 | 0.47 |
| ▸ | ROS1 | P08922 | 3/20 | 0.47 |
| ▸ | FLT3 | P36888 | 3/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30007126 | 1.00 | EGFR (0.53) | EGFRSLC2A1BTKLCKEML4 | |
| SCHEMBL11029146 | 0.86 | SLC2A1 (0.49) | EGFRSLC2A1 | |
| SCHEMBL28862907 | 0.82 | CHEK1 (0.57) | SLC2A1BTKLCKEML4ALK | |
| SCHEMBL30007675 | 0.82 | CHEK1 (0.57) | SLC2A1BTKLCKEML4ALK | |
| SCHEMBL17690587 | 0.76 | SLC2A1 (0.58) | EGFRSLC2A1BTKLCKEML4 | |
| SCHEMBL11031445 | 0.74 | SLC2A1 (0.51) | EGFRSLC2A1BTKBRD4 | |
| SCHEMBL11029346 | 0.74 | MAPKAPK2 (0.61) | EGFRSLC2A1BTKALKFLT3 | |
| SCHEMBL18296155 | 0.74 | LCK (0.73) | EGFRBTKLCKEML4ALK | |
| SCHEMBL25561938 | 0.74 | FLT3 (0.68) | EGFREML4ALKRETROS1 | |
| SCHEMBL16206731 | 0.74 | EGFR (0.77) | EGFRSLC2A1BTKLCKEML4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197132-A | HPK1 inhibitor and application thereof in medicine | 贝达药业股份有限公司 | 2022-10-18 | — | — | CN | disclosed |