SCHEMBL28863271

SCHEMBL28863271

CNO.c1ccc(Cc2ccc[nH]2)cc1

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
IDO1 P14902 1/20 0.43
TAAR1 Q96RJ0 3/20 0.43
HRH3 Q9Y5N1 1/20 0.43
CALM1 P0DP23 1/20 0.41
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
MAOA P21397 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108477 0.90 TAAR1 (0.50) TAAR1HRH3CALM1HPGDTSHR
Hydrochloric Acid SCHEMBL27287864 0.88 TAAR1 (0.48) TAAR1HRH3CALM1HPGDTSHR
Biphenyl SCHEMBL27518037 0.84 HRH3 (0.46) TAAR1HRH3CALM1HPGDTSHR
SCHEMBL29087090 0.80 TAAR1 (0.40) TAAR1HRH3CALM1
Pyridine SCHEMBL28133711 0.79 HRH3 (0.50) TAAR1HRH3CALM1HPGDTSHR
SCHEMBL27647887 0.78 TAAR1 (0.43) IDO1TAAR1HRH3TSHR
Pyridine SCHEMBL28192678 0.78 HRH3 (0.49) TAAR1HRH3CALM1HPGDTSHR
Benzene SCHEMBL28241649 0.76 MAOA (0.45) TSHRMAOA
SCHEMBL23528212 0.76 DAO (0.44) IDO1TAAR1MAOA
SCHEMBL1856737 0.76 TP53 (0.41) TAAR1HRH3MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108529586-A A kind of graphene-based nano carbon microsphere and its preparation method and application 中国科学院过程工程研究所 2018-09-14 CN disclosed