Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13335152 | 0.87 | ATM (0.54) | ATMPBRM1GPR84KMT2AMEN1 | |
| SCHEMBL29885789 | 0.87 | ATM (0.54) | ATMPBRM1GPR84KMT2AMEN1 | |
| SCHEMBL799601 | 0.87 | ATM (0.54) | ATMPBRM1GPR84KMT2AMEN1 | |
| SCHEMBL30437029 | 0.87 | ATM (0.54) | ATMPBRM1GPR84KMT2AMEN1 | |
| SCHEMBL7192679 | 0.83 | ATM (0.50) | ATMPBRM1GPR84KMT2AMEN1 | |
| SCHEMBL11797189 | 0.83 | ATM (0.50) | ATMPBRM1GPR84KMT2AMEN1 | |
| SCHEMBL17232880 | 0.83 | ATM (0.50) | ATMPBRM1GPR84KMT2AMEN1 | |
| SCHEMBL28864004 | 0.82 | ATM (0.52) | ATMPBRM1GPR84KMT2AMEN1 | |
| SCHEMBL23478771 | 0.80 | ATM (0.47) | ATMPBRM1GPR84KMT2AMEN1 | |
| SCHEMBL19059561 | 0.80 | GPR84 (0.47) | ATMGPR84KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328513-A2 | DIINDOLYLMETHANE AND C-SUBSTITUTED DIINDOLYLMETHANE COMPOSITIONS AND METHODS FOR THE TREATMENT OF MULTIPLE CANCERS | The Texas A & M University System (US) | 2003-07-23 | — | — | EP | claimed |
| WO-2002028832-A2 | DIINDOLYLMETHANE AND C-SUBSTITUTED DIINDOLYLMETHANE COMPOSITIONS AND METHODS FOR THE TREATMENT OF MULTIPLE CANCERS | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 2002-04-11 | — | — | WO | claimed |
| EP-0971890-A2 | SUBSTITUTED ANALOGS OF INDOLE-3-CARBINOL AND OF DIINDOLYMETHANE AS ANTIESTROGENS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2000-01-19 | — | — | EP | claimed |
| WO-1998050357-A2 | SUBSTITUTED ANALOGS OF INDOLE-3-CARBINOL AND OF DIINDOLYMETHANE AS ANTIESTROGENS | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 1998-11-12 | — | — | WO | claimed |
| US-9472769-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2016-10-18 | — | — | US | disclosed |
| US-9472769-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2016-10-18 | — | — | US | disclosed |
| CN-103880728-B | A kind of method preparing di-indole methyl hydride compounds | TAIZHOU UNIVERSITY (CN) | 2016-03-30 | — | — | CN | disclosed |
| US-20150263296-A1 | Organic Electroluminescent Device | UDC IRELAND LTD (IE) | 2015-09-17 | — | — | US | disclosed |
| US-20150263296-A1 | Organic Electroluminescent Device | UDC IRELAND LTD (IE) | 2015-09-17 | — | — | US | disclosed |
| US-8890122-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2014-11-18 | — | — | US | disclosed |
| US-8890122-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2014-11-18 | — | — | US | disclosed |
| CN-103880728-A | Method for preparing diindolylmethane compound | UNIV TAIZHOU | 2014-06-25 | — | — | CN | disclosed |
| EP-1811842-A2 | 3,3'-DIINDOLYLMETHANE IMMUNE ACTIVATING COMPOSITIONS | The Regents of the University of California (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006110299-A1 | 3,3'-DIINDOLYLMETHANE COMPOSITIONS INHIBIT ANGIOGENESIS | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-10-19 | — | — | WO | disclosed |
| US-20060229355-A1 | 3.3'-Diindolylmethane compositions inhibit angiogenesis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-10-12 | — | — | US | disclosed |
| WO-2006068713-A2 | 3,3'-DIINDOLYLMETHANE IMMUNE ACTIVATING COMPOSITIONS | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-06-29 | — | — | WO | disclosed |
| EP-1328513-A2 | DIINDOLYLMETHANE AND C-SUBSTITUTED DIINDOLYLMETHANE COMPOSITIONS AND METHODS FOR THE TREATMENT OF MULTIPLE CANCERS | The Texas A & M University System (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002028832-A2 | DIINDOLYLMETHANE AND C-SUBSTITUTED DIINDOLYLMETHANE COMPOSITIONS AND METHODS FOR THE TREATMENT OF MULTIPLE CANCERS | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 2002-04-11 | — | — | WO | disclosed |
| EP-0971890-A2 | SUBSTITUTED ANALOGS OF INDOLE-3-CARBINOL AND OF DIINDOLYMETHANE AS ANTIESTROGENS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998050357-A2 | SUBSTITUTED ANALOGS OF INDOLE-3-CARBINOL AND OF DIINDOLYMETHANE AS ANTIESTROGENS | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 1998-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229355-A1 | 3.3'-Diindolylmethane compositions inhibit angiogenesis | FLT4, FLT1, PGF | ATM 4804/4885PBRM1 1619/4885GPR84 1844/4885 |
| US-20150263296-A1 | Organic Electroluminescent Device | IDO1, L1CAM, IDO2 | ATM 3037/4885PBRM1 3538/4885GPR84 2698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.