Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266298 | 0.98 | LMNA (0.68) | LMNACYP1A2PAOXCYP2D6NFKB1 | |
| SCHEMBL18476686 | 0.98 | LMNA (0.68) | LMNACYP1A2PAOXCYP2D6NFKB1 | |
| SCHEMBL593286 | 0.93 | LMNA (0.61) | LMNACYP1A2PAOXCYP2D6NFKB1 | |
| Hydrochloric Acid SCHEMBL10347010 | 0.91 | LMNA (0.59) | LMNACYP1A2PAOXALDH1A1ALOX15 | |
| SCHEMBL8104259 | 0.89 | LMNA (0.78) | LMNACYP1A2ALDH1A1ALOX15MAPT | |
| SCHEMBL15391 | 0.89 | LMNA (0.78) | LMNACYP1A2ALDH1A1ALOX15MAPT | |
| SCHEMBL495594 | 0.86 | LMNA (0.83) | LMNAALDH1A1MAPTMAPK1GAA | |
| SCHEMBL494255 | 0.86 | LMNA (0.83) | LMNAALDH1A1MAPTMAPK1GAA | |
| SCHEMBL12132118 | 0.86 | LMNA (0.83) | LMNAALDH1A1MAPTMAPK1GAA | |
| SCHEMBL494127 | 0.86 | LMNA (0.83) | LMNAALDH1A1MAPTMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901646-A | Benzotriazine double oxide and pharmaceutical composition thereof | 杭州瑞臻医药有限公司 | 2022-08-12 | — | — | CN | disclosed |