Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11004510 | 0.83 | KMT2A (0.51) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL5690880 | 0.79 | KDM4E (0.45) | KMT2AMEN1CYP2D6LMNAMAPK1 | |
| SCHEMBL4751040 | 0.76 | KDM4E (0.42) | KMT2ACYP2D6LMNAALDH1A1MAPT | |
| SCHEMBL11883845 | 0.74 | CYP2D6 (0.57) | KMT2ACYP2D6SRCLMNAMAPK1 | |
| SCHEMBL5690889 | 0.73 | ALDH1A1 (0.42) | KMT2AMEN1LMNAALDH1A1MME | |
| SCHEMBL74691 | 0.72 | SRC (0.48) | CYP2D6SRCLMNAMAPK1ALDH1A1 | |
| SCHEMBL15203901 | 0.71 | CYP2D6 (0.44) | KMT2ACYP2D6SRCLMNAMAPK1 | |
| SCHEMBL12491230 | 0.71 | CYP2D6 (0.44) | KMT2ACYP2D6SRCLMNAMAPK1 | |
| SCHEMBL2454614 | 0.71 | CYP2D6 (0.52) | KMT2ACYP2D6SRCLMNAMAPK1 | |
| SCHEMBL585192 | 0.71 | CYP2D6 (0.52) | CYP2D6SRCLMNAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530333-A | A kind of preparation method of 4- phenyl -2-Pyrrolidone | 杭州卢普生物科技有限公司 | 2018-09-14 | — | — | CN | disclosed |