Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15447240 | 0.84 | POLB (0.51) | MEN1KMT2APOLBCYP1A2CYP2C9 | |
| SCHEMBL15447242 | 0.84 | POLB (0.51) | MEN1KMT2APOLBCYP1A2CYP2C9 | |
| SCHEMBL18387623 | 0.84 | MEN1 (0.47) | MEN1KMT2APOLBNPSR1CYP1A2 | |
| SCHEMBL660587 | 0.82 | GRIN2B (0.56) | MEN1KMT2APOLB | |
| SCHEMBL24943926 | 0.81 | KDM4E (0.50) | MEN1KMT2ANPSR1CYP2C19ALDH1A1 | |
| SCHEMBL19841946 | 0.80 | MEN1 (0.49) | MEN1KMT2APOLBNPSR1ALDH1A1 | |
| SCHEMBL1128242 | 0.80 | MEN1 (0.71) | MEN1KMT2APOLBNPSR1ALDH1A1 | |
| SCHEMBL28731650 | 0.80 | MEN1 (0.63) | DRD1MEN1KMT2ANPSR1CYP2C19 | |
| SCHEMBL24674629 | 0.78 | DRD4 (0.59) | — | |
| SCHEMBL24251635 | 0.78 | ALDH1A1 (0.59) | MEN1KMT2APOLBNPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244047-A | Indazole derivative and application thereof in medicine | 四川海思科制药有限公司 | 2022-10-25 | — | — | CN | disclosed |