Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 1.00 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.67 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.67 |
| ▸ | KDR | P35968 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29870003 | 1.00 | MET (1.00) | METPDGFRBPDGFRAKDR | |
| SCHEMBL29869923 | 0.94 | MET (1.00) | MET | |
| SCHEMBL28864690 | 0.94 | MET (1.00) | MET | |
| SCHEMBL29870039 | 0.90 | MET (1.00) | MET | |
| SCHEMBL28864784 | 0.90 | MET (1.00) | MET | |
| SCHEMBL28864741 | 0.90 | MET (1.00) | METPDGFRBPDGFRAKDR | |
| SCHEMBL29870327 | 0.90 | MET (1.00) | METPDGFRBPDGFRAKDR | |
| SCHEMBL28864770 | 0.86 | MET (0.83) | MET | |
| SCHEMBL28864772 | 0.85 | MET (0.86) | MET | |
| SCHEMBL29870746 | 0.84 | MET (0.81) | METPDGFRBPDGFRAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107312009-B | Quinoline compound, preparation method, intermediate, pharmaceutical composition and application thereof | 上海医药集团股份有限公司 | 2022-09-20 | — | — | CN | disclosed |