Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.72 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | POLR1A | O95602 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13085882 | 0.85 | HRH3 (0.74) | HRH3CYP11B1CYP11B2 | |
| SCHEMBL2883495 | 0.84 | HRH3 (1.00) | HRH3 | |
| SCHEMBL2892498 | 0.82 | HRH3 (0.71) | HRH3 | |
| SCHEMBL2886483 | 0.82 | HRH3 (0.81) | HRH3CYP11B1CYP11B2ATR | |
| SCHEMBL2883340 | 0.81 | HRH3 (0.98) | HRH3CYP11B1CYP11B2 | |
| SCHEMBL1809750 | 0.74 | HRH3 (0.70) | HRH3ATR | |
| SCHEMBL2884381 | 0.73 | CYP11B1 (0.60) | HRH3CYP11B1CYP11B2 | |
| SCHEMBL1811328 | 0.73 | HRH3 (0.62) | HRH3ATR | |
| SCHEMBL2885714 | 0.72 | HRH3 (0.78) | HRH3CYP11B2ATR | |
| SCHEMBL2887674 | 0.72 | HRH3 (0.78) | HRH3ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820825-B2 | N-substituted-azacyclylamines as histamine-3 antagonists | WYETH LLC (US) | 2010-10-26 | — | — | US | disclosed |