Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627582 | 0.94 | ATM (0.52) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL30849896 | 0.92 | TSHR (0.54) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL1637673 | 0.92 | TSHR (0.54) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL31593156 | 0.89 | ATM (0.62) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11243556 | 0.88 | ATM (0.54) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL20875241 | 0.87 | ATM (0.58) | TSHRALDH1A1HCAR2ATMCYP3A4 | |
| SCHEMBL28872434 | 0.87 | ATM (0.58) | TSHRALDH1A1HCAR2ATMCYP3A4 | |
| SCHEMBL3158164 | 0.87 | ATM (0.46) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL20368914 | 0.85 | HCAR2 (0.45) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8669692 | 0.85 | ATM (0.60) | TSHRALDH1A1HCAR2ATMCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814092-B | Composition for hydrophilic cured product | 三井化学株式会社 | 2018-09-21 | — | — | CN | disclosed |