Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL28865258 | 0.89 | ERN1 (0.74) | ERN1MAPTALDH1A1GAAPOLB | |
| SCHEMBL29924535 | 0.88 | ERN1 (0.96) | ERN1MAPTALDH1A1GAAPOLB | |
| Hydrazine SCHEMBL28550593 | 0.86 | ERN1 (0.93) | ERN1MAPTALDH1A1GAAPOLB | |
| SCHEMBL79298 | 0.86 | ERN1 (1.00) | ERN1MAPTALDH1A1GAAPOLB | |
| SCHEMBL30135697 | 0.86 | ERN1 (1.00) | ERN1MAPTALDH1A1GAAPOLB | |
| SCHEMBL29114875 | 0.85 | ERN1 (0.96) | ERN1MAPTALDH1A1GAAPOLB | |
| Potassium SCHEMBL30661193 | 0.85 | ERN1 (0.96) | ERN1MAPTALDH1A1GAAPOLB | |
| SCHEMBL29114876 | 0.85 | ERN1 (0.96) | ERN1MAPTALDH1A1GAAPOLB | |
| SCHEMBL11417323 | 0.85 | ERN1 (0.96) | ERN1MAPTALDH1A1GAAPOLB | |
| SCHEMBL30661195 | 0.85 | ERN1 (0.96) | ERN1MAPTALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115216891-A | Antibacterial polypropylene melt-blown cloth material and preparation process thereof | 广东春夏新材料科技股份有限公司 | 2022-10-21 | — | — | CN | claimed |