SCHEMBL30135697

SCHEMBL30135697

O=Cc1cc([N+](=O)[O-])ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 1.00
POLB P06746 2/20 0.59
ALDH1A1 P00352 5/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
GPR35 Q9HC97 2/20 0.58
HPGD P15428 2/20 0.58
MAPK1 P28482 2/20 0.58
TP53 P04637 1/20 0.58
TSHR P16473 1/20 0.58
MAPT P10636 5/20 0.58
GAA P10253 2/20 0.58
THRB P10828 1/20 0.56
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
NPC1 O15118 2/20 0.52
LMNA P02545 2/20 0.52
HTT P42858 2/20 0.52
ALPG P10696 1/20 0.52
RECQL P46063 1/20 0.52
TDP1 Q9NUW8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL79298 1.00 ERN1 (1.00) ERN1POLBALDH1A1SMN1; SMN2GPR35
SCHEMBL29114876 0.98 ERN1 (0.96) ERN1POLBALDH1A1SMN1; SMN2GPR35
SCHEMBL11417323 0.98 ERN1 (0.96) ERN1POLBALDH1A1SMN1; SMN2GPR35
SCHEMBL30661195 0.98 ERN1 (0.96) ERN1POLBALDH1A1SMN1; SMN2GPR35
SCHEMBL29924535 0.98 ERN1 (0.96) ERN1POLBALDH1A1SMN1; SMN2GPR35
Potassium SCHEMBL30661193 0.98 ERN1 (0.96) ERN1POLBALDH1A1SMN1; SMN2GPR35
SCHEMBL29114875 0.98 ERN1 (0.96) ERN1POLBALDH1A1SMN1; SMN2GPR35
SCHEMBL11417328 0.98 ERN1 (0.96) ERN1POLBALDH1A1SMN1; SMN2GPR35
Hydrazine SCHEMBL28550593 0.96 ERN1 (0.93) ERN1POLBALDH1A1SMN1; SMN2GPR35
Ethylene SCHEMBL28992810 0.96 ERN1 (0.93) ERN1POLBALDH1A1SMN1; SMN2GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230181773-A1 VISUALIZABLE RADIOACTIVE CARBON MICROSPHERE (CMS), PREPARATION METHOD, AND USE THEREOF Chengdu New Radiomedicine Technology Co., Ltd. (CN) 2023-06-15 US claimed
US-20230149570-A1 METAL NUCLIDE-LOADED CARBON MICROSPHERE (CMS), PREPARATION METHOD, AND USE THEREOF Chengdu New Radiomedicine Technology Co., Ltd. (CN) 2023-05-18 US claimed
US-12533430-B2 Metal nuclide-loaded carbon microsphere (CMS), preparation method, and use thereof Chengdu New Radiomedicine Technology Co., Ltd. (CN) 2026-01-27 US disclosed
EP-3375771-B1 METHOD FOR PRODUCING LACOSAMIDE AND INTERMEDIATE THEREOF UBE CORP (JP) 2025-11-26 EP disclosed
CN-119680014-A Anti-infection bone repair composite material targeting intracellular bacteria and preparation method thereof 广东省科学院微生物研究所(广东省微生物分析检测中心) 2025-03-25 CN disclosed
US-20250002496-A1 INDOLE DERIVATIVES AS A MATRIX DESIGN FRAMEWORK FOR MALDI MASS SPECTROMETRY WITH BROAD APPLICATIONS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA 2025-01-02 US disclosed
US-20230181773-A1 VISUALIZABLE RADIOACTIVE CARBON MICROSPHERE (CMS), PREPARATION METHOD, AND USE THEREOF Chengdu New Radiomedicine Technology Co., Ltd. (CN) 2023-06-15 US disclosed
US-20230149570-A1 METAL NUCLIDE-LOADED CARBON MICROSPHERE (CMS), PREPARATION METHOD, AND USE THEREOF Chengdu New Radiomedicine Technology Co., Ltd. (CN) 2023-05-18 US disclosed
US-11623943-B2 Method for producing lacosamide and intermediate thereof API CORPORATION (JP) 2023-04-11 US disclosed
WO-2022259267-A1 A METHOD FOR OBTAINING L-GLUFOSINATE UPL LIMITED (IN) 2022-12-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533430-B2 Metal nuclide-loaded carbon microsphere (CMS), preparation method, and use thereof CPS1, SRM, NES ERN1 4569/4885POLB 2118/4885ALDH1A1 1172/4885
US-20250002496-A1 INDOLE DERIVATIVES AS A MATRIX DESIGN FRAMEWORK FOR MALDI MASS SPECTROMETRY WITH BROAD APPLICATIONS IDO1, IDO2, AANAT ERN1 4726/4885POLB 2980/4885ALDH1A1 2733/4885
US-11623943-B2 Method for producing lacosamide and intermediate thereof CA3, TREH, NAAA ERN1 2007/4885POLB 2804/4885ALDH1A1 906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.