SCHEMBL28865612

SCHEMBL28865612

CC1COC(c2ccccc2)O1.c1ccc(COCc2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
CYP2C19 P33261 1/20 0.39
ALDH1A1 P00352 1/20 0.38
ADRA1A P35348 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12944479 0.85 MEN1 (0.50) TSHRMEN1KMT2AL3MBTL1CYP2C19
SCHEMBL12944476 0.85 MEN1 (0.50) TSHRMEN1KMT2AL3MBTL1CYP2C19
SCHEMBL531471 0.85 MEN1 (0.50) TSHRMEN1KMT2AL3MBTL1CYP2C19
Propylene Oxide SCHEMBL335355 0.82 TSHR (0.62) TSHRMEN1KMT2AL3MBTL1CYP2C19
Propylene Oxide SCHEMBL335357 0.82 TSHR (0.62) TSHRMEN1KMT2AL3MBTL1CYP2C19
SCHEMBL11329778 0.76 CYP11B1 (0.40) TSHRMEN1KMT2AL3MBTL1CYP2C19
SCHEMBL12677784 0.75 TAAR1 (0.46) TSHRMEN1KMT2ACYP2C19TAAR1
SCHEMBL5100543 0.73 SLC6A2 (0.46) TSHRL3MBTL1TAAR1LMNA
SCHEMBL14747307 0.73 SLC6A2 (0.46) TSHRL3MBTL1TAAR1LMNA
SCHEMBL7720184 0.73 BCHE (0.49) MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108601958-A Pro-perfume compositions 爱客多有限公司 2018-09-28 CN disclosed