Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GJB2 | P29033 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5100543 | 1.00 | SLC6A2 (0.46) | SLC6A2BCHEACHEPDE4DHTR1A | |
| SCHEMBL21964247 | 0.85 | SLC6A2 (0.49) | SLC6A2BCHEPDE4DL3MBTL1TSHR | |
| SCHEMBL7720184 | 0.82 | BCHE (0.49) | SLC6A2BCHEL3MBTL1 | |
| SCHEMBL18689878 | 0.82 | BCHE (0.49) | SLC6A2BCHEL3MBTL1 | |
| SCHEMBL10592401 | 0.80 | TSHR (0.48) | SLC6A2BCHEACHEPDE4DHTR1A | |
| SCHEMBL21874108 | 0.80 | L3MBTL1 (0.35) | SLC6A2BCHEPDE4DL3MBTL1 | |
| SCHEMBL14432278 | 0.78 | REN (0.41) | SLC6A2GJB2 | |
| SCHEMBL22316285 | 0.78 | BCHE (0.55) | SLC6A2BCHEACHEPDE4DHTR1A | |
| SCHEMBL13446337 | 0.78 | BCHE (0.55) | SLC6A2BCHEACHEPDE4DHTR1A | |
| SCHEMBL19380966 | 0.78 | BCHE (0.55) | SLC6A2BCHEACHEPDE4DHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |