Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 18/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15648646 | 0.85 | RORC (0.59) | RORC | |
| SCHEMBL28846685 | 0.81 | RORC (0.57) | RORCNOTUM | |
| SCHEMBL28846682 | 0.80 | DRD4 (0.48) | RORCMAPTNOTUM | |
| SCHEMBL15647666 | 0.78 | RORC (0.53) | RORC | |
| SCHEMBL28158206 | 0.75 | ELANE (0.36) | RORCMAPT | |
| SCHEMBL16632547 | 0.75 | RORC (0.65) | RORC | |
| SCHEMBL15647668 | 0.75 | RORC (0.60) | RORC | |
| SCHEMBL16632822 | 0.75 | RORC (0.60) | RORC | |
| SCHEMBL28158208 | 0.74 | RORC (0.48) | RORC | |
| SCHEMBL15647983 | 0.74 | RORC (0.65) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829294-B | The quinolyl conditioning agent of ROR- γ-T being connect with methylene | 詹森药业有限公司 | 2018-11-09 | — | — | CN | disclosed |