Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 8/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270534 | 0.86 | CYP1A2 (0.81) | ALDH1A1RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL3128331 | 0.86 | CYP1A2 (0.81) | ALDH1A1RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL13030714 | 0.86 | CYP1A2 (0.81) | ALDH1A1RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL29176317 | 0.84 | RECQL (1.00) | ALDH1A1RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL446006 | 0.84 | RECQL (1.00) | ALDH1A1RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL425338 | 0.84 | RECQL (1.00) | ALDH1A1RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL23251385 | 0.82 | MAPT (0.81) | ALDH1A1RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL12275056 | 0.81 | RECQL (0.79) | ALDH1A1RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL12275054 | 0.81 | RECQL (0.79) | ALDH1A1RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL782731 | 0.81 | MAPT (1.00) | ALDH1A1RAB9ASMN1; SMN2NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215796-B | Synthesis method of 3-acyl quinoline compound | 江南大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-115215796-A | Synthetic method of 3-acyl quinoline compound | 江南大学 | 2022-10-21 | — | — | CN | disclosed |