Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 5/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 6/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.50 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18775012 | 0.81 | SLC1A2 (0.50) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL25006937 | 0.81 | SLC1A2 (0.50) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL18775024 | 0.81 | SLC1A2 (0.50) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL18775019 | 0.81 | SLC1A2 (0.50) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL28202345 | 0.81 | PTGS1 (0.45) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL28251125 | 0.81 | SLC1A2 (0.42) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL28250555 | 0.81 | SLC1A2 (0.42) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL28250558 | 0.79 | SLC1A2 (0.41) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL13968330 | 0.79 | SLC1A2 (0.47) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL23836642 | 0.77 | GRIK1 (0.51) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130871-B | A kind of sulfur derivatives and its preparation method and application of pyrrolin ketone | 南京农业大学 | 2018-11-09 | — | — | CN | disclosed |