SCHEMBL28250558

SCHEMBL28250558

CCCCC(S)(CC(N)C(=O)O)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 6/20 0.41
SLC1A1 P43005 5/20 0.41
SLC1A3 P43003 5/20 0.41
KIF11 P52732 1/20 0.40
GRIK1 P39086 5/20 0.40
GRIK2 Q13002 4/20 0.40
SLC7A5 Q01650 1/20 0.37
DDAH1 O94760 2/20 0.36
PTGS1 P23219 2/20 0.35
SLC7A11 Q9UPY5 1/20 0.35
MAPT P10636 2/20 0.33
NOS1 P29475 2/20 0.33
ALDH1A1 P00352 1/20 0.33
SLC15A1 P46059 1/20 0.33
NOD1 Q9Y239 1/20 0.33
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28250630 0.87 SLC1A2 (0.39) SLC1A2SLC1A1SLC1A3KIF11GRIK1
SCHEMBL28865883 0.79 SLC1A2 (0.51) SLC1A2SLC1A1SLC1A3KIF11GRIK1
SCHEMBL28251125 0.78 SLC1A2 (0.42) SLC1A2SLC1A1SLC1A3KIF11GRIK1
SCHEMBL28250555 0.78 SLC1A2 (0.42) SLC1A2SLC1A1SLC1A3KIF11GRIK1
SCHEMBL28042077 0.77 KIF11 (0.38) SLC1A2SLC1A1SLC1A3KIF11GRIK1
Hydrochloric Acid SCHEMBL7410774 0.76 SLC1A2 (0.43) SLC1A2SLC1A1SLC1A3KIF11GRIK1
SCHEMBL25006937 0.75 SLC1A2 (0.50) SLC1A2SLC1A1SLC1A3KIF11GRIK1
SCHEMBL18775019 0.75 SLC1A2 (0.50) SLC1A2SLC1A1SLC1A3KIF11GRIK1
SCHEMBL18775012 0.75 SLC1A2 (0.50) SLC1A2SLC1A1SLC1A3KIF11GRIK1
SCHEMBL18775024 0.75 SLC1A2 (0.50) SLC1A2SLC1A1SLC1A3KIF11GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105130871-B A kind of sulfur derivatives and its preparation method and application of pyrrolin ketone 南京农业大学 2018-11-09 CN disclosed