SCHEMBL28865989

SCHEMBL28865989

CCc1ccc(Cc2ccccc2)c(CC)c1CC

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.48
CALM1 P0DP23 1/20 0.46
BCL2 P10415 1/20 0.43
BCL2L1 Q07817 1/20 0.43
CTRC Q99895 3/20 0.43
ALOX5 P09917 1/20 0.42
HTR2A P28223 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL28528486 0.96 TP53 (0.44) TP53CALM1BCL2BCL2L1CTRC
Hydrochloric Acid SCHEMBL28790599 0.96 TP53 (0.44) TP53CALM1BCL2BCL2L1CTRC
SCHEMBL27512807 0.91 TP53 (0.48) TP53CALM1BCL2BCL2L1CTRC
SCHEMBL11843990 0.91 TP53 (0.48) TP53CALM1BCL2BCL2L1CTRC
SCHEMBL31167415 0.91 TP53 (0.48) TP53CALM1BCL2BCL2L1CTRC
SCHEMBL6546008 0.89 TP53 (0.46) TP53CALM1BCL2BCL2L1HTR2A
SCHEMBL11203713 0.86 HTR2A (0.46) TP53CALM1BCL2BCL2L1HTR2A
SCHEMBL10601277 0.85 TP53 (0.46) TP53CALM1BCL2BCL2L1HTR2A
SCHEMBL10599555 0.84 TP53 (0.50) TP53CALM1BCL2BCL2L1HTR2A
SCHEMBL24941694 0.83 TP53 (0.44) TP53CALM1BCL2BCL2L1CTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108659203-A A kind of Maleic anhydride fimctionalized liquid polybutadiene modified epoxy and its preparation method and application 上海腾巽新材料有限公司 2018-10-16 CN claimed
CN-108659203-A A kind of Maleic anhydride fimctionalized liquid polybutadiene modified epoxy and its preparation method and application 上海腾巽新材料有限公司 2018-10-16 CN disclosed