SCHEMBL6546008

SCHEMBL6546008

CCc1cccc(Cc2ccccc2)c1CC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.46
CALM1 P0DP23 1/20 0.44
HTR2A P28223 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.42
BCL2 P10415 1/20 0.42
BCL2L1 Q07817 1/20 0.42
GABRA1 P14867 2/20 0.41
GABRB2 P47870 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
LTA4H P09960 1/20 0.41
DRD2 P14416 1/20 0.40
DRD1 P21728 1/20 0.40
DRD3 P35462 1/20 0.40
PTPN1 P18031 1/20 0.40
ALDH1A1 P00352 1/20 0.40
ALOX12 P18054 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11203713 0.96 HTR2A (0.46) TP53CALM1HTR2AL3MBTL1BCL2
SCHEMBL10599555 0.96 TP53 (0.50) TP53CALM1HTR2AL3MBTL1BCL2
SCHEMBL10601277 0.92 TP53 (0.46) TP53CALM1HTR2AL3MBTL1BCL2
SCHEMBL28865989 0.89 TP53 (0.48) TP53CALM1HTR2AL3MBTL1BCL2
Ethylbenzene SCHEMBL9864115 0.87 TP53 (0.64) TP53GABRA1GABRB2ALDH1A1ALOX12
SCHEMBL5250861 0.87 TP53 (0.50) TP53CALM1HTR2AL3MBTL1BCL2
SCHEMBL9746190 0.86 TP53 (0.44) TP53CALM1HTR2ABCL2BCL2L1
Bromide SCHEMBL28528486 0.86 TP53 (0.44) TP53CALM1HTR2AL3MBTL1BCL2
Hydrochloric Acid SCHEMBL28790599 0.86 TP53 (0.44) TP53CALM1HTR2ABCL2BCL2L1
SCHEMBL31167415 0.85 TP53 (0.48) TP53CALM1HTR2AL3MBTL1BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
EP-0708077-B1 Diamino compounds and methods for preparing them CHISSO CORP (JP) 2000-12-27 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
US-5663440-A Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1997-09-02 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
EP-0708077-A1 Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1996-04-24 EP disclosed