SCHEMBL28866147

SCHEMBL28866147

C=CCCCC[SiH2]OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL706692 0.82
SCHEMBL1228829 0.81 TSHR (0.38) TSHRALDH1A1LMNA
SCHEMBL1229845 0.81 TSHR (0.38) TSHRALDH1A1LMNA
SCHEMBL1229969 0.81 TSHR (0.38) TSHRALDH1A1LMNA
SCHEMBL8514523 0.81 TSHR (0.38) TSHRALDH1A1LMNA
SCHEMBL8514129 0.81 TSHR (0.38) TSHRALDH1A1LMNA
SCHEMBL1229649 0.81 TSHR (0.38) TSHRALDH1A1LMNA
SCHEMBL1228259 0.81 TSHR (0.38) TSHRALDH1A1LMNA
SCHEMBL929341 0.79
SCHEMBL1123039 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105593234-B Novel organopolysiloxane, the surface conditioning agent comprising it, the resin combination comprising it and their gel-like product or cured product 道康宁东丽株式会社 2018-10-26 CN disclosed