SCHEMBL28866299

SCHEMBL28866299

CCCCCN(Cl)Cc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 5/20 0.50
SIGMAR1 Q99720 3/20 0.44
CNR2 P34972 2/20 0.43
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
DRD2 P14416 2/20 0.43
OPRM1 P35372 2/20 0.43
DRD3 P35462 2/20 0.43
OPRD1 P41143 2/20 0.43
OPRK1 P41145 2/20 0.43
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1691958 0.98 KCNH2 (0.53) KCNH2SIGMAR1CNR2DRD2OPRM1
SCHEMBL18597659 0.98 KCNH2 (0.53) KCNH2SIGMAR1CNR2DRD2OPRM1
Hydrochloric Acid SCHEMBL28371828 0.96 KCNH2 (0.51) KCNH2SIGMAR1CNR2DRD2OPRM1
SCHEMBL28028325 0.94 TDP1 (0.46) KCNH2SIGMAR1ALDH1A1TSHRDRD2
Hydrochloric Acid SCHEMBL6640845 0.84 TSHR (0.48) SIGMAR1CNR2ALDH1A1TSHR
SCHEMBL9013394 0.81 KCNH2 (0.70) KCNH2SIGMAR1DRD2OPRM1DRD3
SCHEMBL22870759 0.80 KCNH2 (0.62) KCNH2DRD2OPRM1DRD3OPRD1
SCHEMBL9484533 0.80 KCNH2 (0.62) KCNH2DRD2OPRM1DRD3OPRD1
SCHEMBL10938303 0.80 SIGMAR1 (0.37) KCNH2SIGMAR1CNR2ALDH1A1TSHR
SCHEMBL16687557 0.80 RARB (0.54) CNR2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104969406-B Electrolyte solution for electrochemical device and electrochemical device 富士胶片和光纯药株式会社 2018-11-02 CN disclosed