SCHEMBL28866705

SCHEMBL28866705

C1=CC=CNC=C1.NC(=O)NC(N)=O

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.38
TSHR P16473 2/20 0.32
NFKB1 P19838 2/20 0.32
LMNA P02545 2/20 0.32
CYP1A2 P05177 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
THPO P40225 1/20 0.32
CA2 P00918 1/20 0.32
CYP3A4 P08684 1/20 0.32
CA5A P35218 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
CA9 Q16790 1/20 0.32
PEPD P12955 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazinecarboxamide SCHEMBL28077095 0.84 TSHR (0.53) TSHRNFKB1LMNACYP1A2MAOA
Carbamic Acid SCHEMBL27422028 0.80 ACHE (0.44)
Carbamic Acid SCHEMBL28313671 0.78 ACHE (0.41)
Hydroxyamine SCHEMBL5061248 0.73
SCHEMBL27942910 0.73
SCHEMBL27560286 0.72 CRBN (0.60) CRBNTSHRNFKB1LMNACYP1A2
SCHEMBL27524722 0.72 CRBN (0.60) CRBNTSHRNFKB1LMNACYP1A2
SCHEMBL15045 0.72
SCHEMBL27939070 0.72 CRBN (0.60) CRBNTSHRNFKB1LMNACYP1A2
Urea SCHEMBL1497927 0.69 CRBN (0.56) CRBNTSHRNFKB1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108997336-A A kind of azepine imide compound and organic light-emitting display device 上海天马有机发光显示技术有限公司 2018-12-14 CN claimed
CN-108997336-A A kind of azepine imide compound and organic light-emitting display device 上海天马有机发光显示技术有限公司 2018-12-14 CN disclosed